VisionGate Receives Strategic Investment from Trinnovate Ventures

Partnership Tackles Lung Cancer, the No. 1 Cancer Killer Throughout the World

PHOENIX, Ariz. (March 16, 2016) – Trinnovate Ventures today announced it will partner with Phoenixbased VisionGate to help accelerate clinical trial programs for both LuCED, a non-invasive diagnostic test targeting early stage lung cancer that responds best to therapy, and Iloprost, a chemoprevention drug for patients who have a pre-cancerous condition of the lungs called dysplasia.

Trinnovate Ventures, a subsidiary of Blue Cross Blue Shield (BCBS) of Arizona, seeks collaborations that promise to ultimately deliver the triple aim of lower healthcare costs, improved patient outcomes and better patient experiences.

“Lung cancer is the number one cancer killer worldwide and is the only cancer whose five-year survival rate has remained virtually unchanged for decades due to the lack of an effective screening test that could significantly impact survival, while other cancers have benefited from a mammogram, Pap smear, colonoscopy, or PSA,” Trinnovate’s Chief Executive Officer and BCBS of Arizona’s Chief Medical Officer Dr. Vishu Jhaveri said. “VisionGate’s accurate LuCED test for lung cancer and dysplasia, along with the company’s exclusive rights to Iloprost, a therapeutic drug that has exhibited in Phase 2 clinical trials the ability to reverse pre-cancerous dysplasia to prevent lung cancer, demonstrates incredible promise.”

As part of this collaboration, Trinnovate Ventures will serve as the lead investor for VisionGate’s $20- million funding round. Having evaluated VisionGate for over a year, Trinnovate’s strategic investment underscores VisionGate’s potential in the marketplace to significantly impact lung cancer mortality and bring a new paradigm for the management of this terrible disease. The partnership will propel the clinical research forward in hopes that Arizonans and people around the world will have quicker access to VisionGate’s potentially life-saving diagnostic and therapeutic innovations.

“Our focus is on finding lung cancer early – when patients are pre-symptomatic, but when treatment is most effective. This is how we start eradicating lung cancer,” VisionGate’s Chairman and CEO Dr. Alan Nelson said. “Our partnership with Trinnovate is pivotal and accelerates our effort to lower healthcare costs through the application of our patented technologies that hold potential to dramatically alter the course of lung cancer, including its prevention.”

For more information about VisionGate, please visit www.visiongate3d.com.

About VisionGate

VisionGate, Inc. is led by Dr. Alan Nelson, physicist, bioengineer and entrepreneur who previously developed the world’s first and only automated screening test to detect cervical cancer, marketed globally today as FocalPoint by Becton Dickinson. VisionGate’s proprietary LuCED test is a non-invasive diagnostic test for early-stage lung cancer, demonstrating exquisite sensitivity and specificity in blinded clinical studies. This physician-ordered, take-home sputum test is processed on the world’s first 3D cell imaging platform, the Cell-CT, named aptly because it is similar in principle to taking a CT scan of individual cells, but using visible light without harmful radiation. Moreover, with the new exclusive patent license from the University of Colorado for the drug called Iloprost, VisionGate will drive the therapeutic market for chemoprevention of lung cancer and, ultimately, the eradication of this killer. With 140 issued patents in 13 countries, VisionGate expects to play a leading role in the battle against the world’s number one cancer killer.

About Trinnovate

Ventures Trinnovate Ventures makes investments in healthcare innovations that incorporate three crucial components (the “TRI” in Trinnovate). These pillars of investment are partnership, collaboration and results. Together, these embody the mission statement of Blue Cross Blue Shield of Arizona, which is to provide the best value in health insurance and improve the quality of life for Arizonans.