City of Phoenix
VisionGate, in collaboration with the City of Phoenix, has created the 3D Cellular Imaging Lab based on VisionGate’s 3D cellular imaging platform, the Cell-CT. The mission of the new lab is to make VisionGate’s technology available to Arizona researchers whose work could be enabled by the Cell-CT. Researchers who are interested in using the lab first submit a request for proposals to VisionGate who reviews the proposal to assess technical compatibility with the Cell-CT instruments. Accepted proposals then go on for review to assess scientific merit by an advisory board, comprised of leaders within the scientific community who represent academia, clinical practice and private industry.
Human Photonics Lab
Statement from Prof. Eric Seibel
The Human Photonics Laboratory (HPL) is a lab devoted to innovation of medical devices and instrumentation at the University of Washington. The HPL is focused on the early detection of disease and their treatments, with special emphasis on lung cancer which is a curable disease if diagnosed and treated early. The basis of HPL technologies have been combining optics with mechanics and image processing. The HPL expertise comes from its multi-disciplinary nature, inventiveness, and collaboration with industry. In 2002-2004, HPL director Eric Seibel and Alan Nelson co-lead the development of the first prototype Cell-CT instrument with pilot funding from the Washington Technology Center. In the following years, technical accomplishments were performed and published as a VisionGate-HPL team, such as (1) demonstration of improvement in sensitivity of cancer diagnosis when imaging cells in 3D versus 2D (Meyer et al., 2009), (2) co-registered 3D images of both fluorescence and absorption stain of chromatin within a single cell (Miao et al., 2009 and UW Press Release: Cancer diagnosis: Now in 3-D. Future work is toward more quantitative measures of cancer features within single cells using this multimodal Cell-CT approach using fluorescence and absorption 3D imaging (funding from the National Science Foundation).