Cell-CT™ 3-Dimensional Cell Imaging and Analysis Process


The LuCED® Lung Test Processing

The Cell-CT™ platform is an automated 3D imaging technology critical to the processing of the LuCED® lung test because it uses a technique called Optical Projection Tomography to render cells to be visible in 3D. This process is illustrated for a squamous cancer cell in the video below where a cell is shown transported through a glass micro-capillary disposal by applying pressure to a gel that embeds cells. As the capillary spins, the cell is scanned from multiple perspectives yielding a set of pseudo-projection images. These images are combined together using a method known as Filtered Back-Projection, producing the final 3D cell volume.

Color and opacity may be adjusted in the reconstruction to emphasize aspects of the cell that are of interest. This process is shown for a ciliated columnar cell.

The cell is shown in maximum intensity projection. In the center and right panels, color and opacity have been adjusted to render the cytoplasm in translucent white, the nucleus in opaque blue and the interior of the nucleus in a green to red chromatic gradient with the nucleoli rendered in opaque red. The cell is shown whole at left and center and cropped at right. Individual cillia are approximately 0.2 microns in diameter. Observation of individual cilia in the video indicates that resolution is at least one-half micron.


This website may contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and made in reliance on the "safe harbor" provisions of said act. Forward-looking statements are based on estimates, projections, beliefs and assumptions of VisionGate® management at the time of such statements and are not guarantees of future performance. Forward-looking statements involve risks and uncertainties in predicting future results and conditions. Actual results could differ materially from those projected in these forward-looking statements due to a variety of factors, including, without limitation, the acceptance by customers of our products, our ability to develop new products cost-effectively, our ability to raise capital in the future, the development by competitors of products using improved or alternative technology, the retention of key employees and general economic conditions. Forward-looking statements are subject to change without notice.

Contact Us

If you are interested in learning more about VisionGate and would like to speak with someone, please complete this short inquiry form and a representative will contact you as soon as possible.


Copyright 2017 - VisionGate, Inc.